Liza Dahal

Postdoctoral Researcher

                      


Transcription factors comprise approximately 7-10% of the human proteome and are crucial players in orchestrating multiple cellular processes. An array of post transcriptional modifications (PTMs) including phosphorylation, acetylation, glycosylation and SUMOylation, decorate these proteins allowing tight regulation of gene expression. Cross-talk between these PTMs provide an added layer of complexity to transcription factor interactions resulting in unique functional output for specific interactions driven by PTMs. My current goal is to develop in vivo approaches to study the role of PTMs in interactions and dynamics of transcription factors.