Sequence specific DNA-binding transcription factors (TFs) are seminal players in eukaryotic gene regulation.
Dynamic and selective low-complexity domain interactions and their roles in transcription and cancer
During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are excluded from chromosomes. How do daughter cells re-establish the original transcription...
Mitotic Bookmarking by Transcription Factors
Mammalian interphase genomes are functionally compartmentalized into topologically associating domains (TADs) spanning hundreds of kilobases.
Dynamics of 3D genome organization: the role of CTCF and cohesin